Triazolobenzodiazepines (TBZD) are a class of benzodiazepine (BZD) derivative pharmaceutical drugs. Chemically, they differ from other benzodiazepines by having an additional triazole ring fused to the diazepine ring. The triazole and diazepine rings share a nitrogen atom.

Examples include:

Adinazolam
Alprazolam
Bromazolam
Clonazolam
Estazolam
Flualprazolam
Flubromazolam
Flunitrazolam
Nitrazolam
Pyrazolam
Triazolam
Zapizolam
Synthesis
Synthesis of 1-methyltriazolobenzodiazepines (alprazolam type) is possible by heating 1,4-benzodiazepin-2-thiones with hydrazine and acetic acid in n-butanol under reflux.[1]