It is a Synthetic cannabinoids, or neocannabinoids, are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and many others) in cannabis plants attach.[1] These novel psychoactive substances should not be confused with synthetic phytocannabinoids (obtained by chemical synthesis) or synthetic endocannabinoids from which they are distinct in many aspects.[2][3][4]
Typically, synthetic cannabinoids are sprayed onto plant matter[5] and are usually smoked,[6] although they have also been ingested as a concentrated liquid form in the United States and United Kingdom since 2016.[7] They have been marketed as herbal incense, or “herbal smoking blends”,[6] and sold under common names such as K2, spice,[8] and synthetic marijuana.[5] They are often labeled “not for human consumption” for liability defense.[8] A large and complex variety of synthetic cannabinoids are designed in an attempt to avoid legal restrictions on cannabis, making synthetic cannabinoids designer drugs.[6]








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